Discipline 01
Architecture & GMP layout
Space planning, cleanroom construction, wall/ceiling/floor systems, doors and pass-throughs, and the flows that keep contamination out.
Space planning, cleanroom construction, wall/ceiling/floor systems, doors and pass-throughs, and flows that keep contamination out. We design the envelope around the process.
- 01ArchitectureEnvelope, roof plant, access(this discipline)
- 02HVAC
- 03Electrical
- 04Utilities / Plumbing
- 05Fire Fighting
- 06CleanroomsGMP zoning, flows, classification(this discipline)
- 07Automation / BMS
- 08Process Equipments
GMP layout & flows
Zoned around the process.
Every room is zoned to its cleanliness grade and HVAC class, with defined temperature and humidity limits and a pressure cascade that keeps air moving from clean to less clean.
| Zone | Conditions |
|---|---|
| Grade D | 22 ± 3 °C · RH not more than 55% |
| Grade C | 22 ± 3 °C · RH not more than 55% |
| Comfort | Not more than 27 °C |
Isolator-based filling
Powder and liquid filling take place in isolators within a Grade C room.
Graded support rooms
Preparation, washing and process rooms zoned by product exposure.
Comfort & technical zones
Packing, stores and corridors comfort-cooled; technical areas ventilated.
Five layers, one facility.
A pharmaceutical facility only works when every system works together. We design each discipline in-house and coordinate them as one, so the facility performs as a whole, not as a set of parts.
- Process & equipmentPFDs, fully annotated P&IDs, equipment specification, sizing and layout.
- HVAC & air handlingAHU-wise ducting, supply and return balancing, pressure cascades and area classification.
- Clean & black utilitiesPW, WFI, clean steam and gases on the clean side; chilled water, chillers and compressed air on the black side.
- Electrical & automationPower distribution, cable trays, lighting to lux targets, control panels and monitoring.
Let’s design it right.
From the first concept sketch to an issued-for-construction package, Agon designs pharmaceutical facilities that meet the highest international standards. We would welcome the conversation.